Logitech MX Vertical review

The MX Vertical is the pick for people with bigger hands who want the vertical posture of the Lift. Logitech uses the same 57° angle and says the handshake position reduces muscular strain by 10 percent and that the design was tested against criteria set by ergonomists for posture, muscle strain and wrist pressure. A cursor speed switch on the mouse lets you raise sensitivity so the hand moves less, which Logitech puts at 4x less hand movement. The battery is a rechargeable 240 mAh Li-Po cell rated for up to 4 months, and a one-minute charge gives 3 hours of use, so a flat battery never stops a work day. It connects through the Unifying USB receiver, Bluetooth or the USB-C cable, and pairs with up to three devices. It weighs 125 g. The trade-offs: there is no left-handed version, the receiver is the older Unifying type, and the $99.99 price we saw was a $20 discount on the $119.99 list price.

Who it is for

medium to large hands that want a rechargeable vertical mouse

Price

$99.99 on sale, list $119.99.

Advanced Ergonomic Mouse 471 $99.99 $119.99 $20.00 off
Quoted from the vendor pricing page on November 13, 2026.

Key features

• 57° vertical angle that Logitech says reduces pressure on the wrist
• Natural handshake position that Logitech says reduces muscular strain by 10 percent
• Cursor speed switch that Logitech says gives 4x less hand movement
• Rechargeable 240 mAh Li-Po battery rated for up to 4 months, with 3 hours from a 1-minute charge
• Connects by Unifying USB receiver, Bluetooth Low Energy or the USB-C charging cable, and pairs up to 3 devices

Strengths and weaknesses

• Strength: Sized for medium to large hands, which the Lift is not
• Strength: One-minute quick charge gives 3 hours of use
• Strength: Logitech lists a 10 percent reduction in muscular strain from the handshake position
• Weakness: Right-handed only, with no left-handed version listed
• Weakness: Uses the older Unifying receiver rather than Logi Bolt
• Weakness: $99.99 was a sale price; the list price is $119.99

Key facts

• Price: $99.99 on sale, list $119.99
• Grip angle: 57° vertical
• Hand size: Medium to large
• Battery: Rechargeable, up to 4 months
• Weight: 4.41 oz (125 g)

Where it ranks

Logitech MX Vertical is No. 2 in our Best Ergonomic Mice verdict.