Florastor Dual Action Probiotic Supplement review

Florastor is the yeast pick on this list. Its only active strain is Saccharomyces boulardii CNCM I-745, and the brand says no other product contains it, citing 70 years of safe use and over 1,000 publications. The product page describes the mechanism plainly: unwanted bacteria bind to the yeast and are flushed out, leaving room for good bacteria. Prices step down with size, from $19.82 for 20 capsules to $28.97 for 30, $39.99 for 50 and $67.99 for 100, which is about $0.68 a capsule at the largest size. Capsules are gluten-free, vegetarian and non-GMO, and orders of $24.99 or more ship free. Florastor is also sold at Amazon, Walmart, Target, Walgreens and CVS. The small box is pricey per capsule, and like Culturelle it is a single-strain product without a prebiotic, so it suits people who want this specific yeast more than a broad blend.

Who it is for

people who want a probiotic yeast rather than bacteria

Price

$19.82 for 20 capsules; 30 ct $28.97, 50 ct $39.99, 100 ct $67.99; free shipping from $24.99.

20 ct $19.82
Quoted from the vendor pricing page on November 13, 2026.

Key features

• Saccharomyces boulardii CNCM I-745, a probiotic yeast
• Box sizes of 20, 30, 50 and 100 capsules
• Gluten-free, vegetarian and non-GMO
• Florastor cites 70 years of safe use and over 1,000 publications on the strain
• Also sold at Amazon, Walmart, Target, Walgreens and CVS

Strengths and weaknesses

• Strength: The 100-count box cuts the price to about $0.68 a capsule
• Strength: A yeast strain, which Florastor says is the only product containing CNCM I-745
• Strength: Free shipping on orders of $24.99 and up
• Weakness: The 20-count box costs about $0.99 a capsule, well above Culturelle
• Weakness: Only one strain, with no prebiotic in this formula
• Weakness: Not a synbiotic: Florastor sells prebiotic fiber in a separate Advanced Pro + Pre product

Key facts

• Strain: Saccharomyces boulardii CNCM I-745
• Sizes: 20, 30, 50, 100 capsules
• Diet: Gluten-free, vegetarian, non-GMO
• Research: Over 1,000 publications on the strain, per Florastor
• Free shipping: Orders $24.99 and up

Where it ranks

Florastor Dual Action Probiotic Supplement is No. 3 in our Best Probiotics verdict.